Adverse Reaction Terms

Links to websites that explain the clinical entities behind the terms/concepts found in adverse reaction lists.

The links on this page are intended for regulatory affairs and labeling professionals looking for basic information on the "clinical meaning" of adverse reaction/event terms.

Proposed term definitions for regulatory reporting purposes (a slightly different perspective) can be found in the CIOMS publication "Reporting Adverse Drug Reactions: Definitions of Terms and Criteria for Their Use 1999. ISBN 92 9036 071 2" (out of print).

Pharmiceutics LLC does not does not guarantee the correctnes and up-to-dateness of the information on the websites linked below. There may be better websites out there; please feel free to suggest different/additional links. Some of the liks have been selected because of the quality of images.

Always keep in mind that the clinical characteristics of a reaction to a specific medicine may differ from the description found on these websites, both in general aspects and in individual persons.

Click on a term.

Anaphylaxis, anaphylactic reaction, anaphylactoid reaction: Link 1 - Link 2
Note that there is inconsistent use of terminology in the medical community both in English speaking countries and other countries. The linked articles have been selected because of their careful (but not identical) use of terminology. Another good - but not perfect - explanation of the "terminology around anaphylaxis" is found in the CIOMS publication cited aboove.
Angioedema
Erythema multiforme (for SJS and TEN see also below)
Erythema nodosum
Liver reactions
Stevens Johnson Syndrome (SJS)
Toxix epidermal necrolysis (TEN)
Uricaria, hives

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